Comparison of Quantification of Target-Specific Accumulation of [<sup>18</sup>F]F-siPSMA-14 in the HET-CAM Model and in Mice Using PET/MRI

Comparison of Quantification of Target-Specific Accumulation of [<sup>18</sup>F]F-siPSMA-14 in the HET-CAM Model and in Mice Using PET/MRI

Assessment of biodistribution and specific tumor accumulation is essential for the development of new radiopharmaceuticals and requires animal experiments. The HET-CAM (hens-egg test—chorioallantoic membrane) model can be used in combination with the non-invasive imaging modalities PET and MRI for p...

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Bibliographic Details
Main Authors: Jessica Löffler, Carmen Hamp, Ellen Scheidhauer, Daniel Di Carlo, Christoph Solbach, Alireza Abaei, Li Hao, Gerhard Glatting, Ambros J. Beer, Volker Rasche, Gordon Winter
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
PSMA
HET-CAM
chick embryo
PET
MRI
fluoride ligand
Online Access:https://www.mdpi.com/2072-6694/13/16/4007

Internet

https://www.mdpi.com/2072-6694/13/16/4007

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