Cisplatin inhibits the proliferation of Saos-2 osteosarcoma cells via the miR-376c/TGFA pathway

Cisplatin inhibits the proliferation of Saos-2 osteosarcoma cells via the miR-376c/TGFA pathway

The transforming growth factor alpha (TGFA) gene is involved in the proliferation and metastasis of various tumors, but its role in cell sensitivity to cisplatin chemotherapy is unclear. In this study, we investigated the mechanism underlying inhibitory effects of cisplatin on growth and proliferat...

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Bibliographic Details
Main Authors: Yuan Wang, Yichao Wu, Awei Cai, Chengxiao Ma, Shang Cai, Hao Wang, Yukang Que, Shenglin Xu, Tangbing Xu, Yong Hu
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021-04-01
Series:Biomolecules & Biomedicine
Subjects:
Cisplatin
miR-376c
transforming growth factor alpha
TGFA
Saos-2
cell proliferation
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4485

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/4485

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