The somatic mutation profile of estrogen receptor-positive HER2-negative metastatic breast cancer in Brazilian patients

The somatic mutation profile of estrogen receptor-positive HER2-negative metastatic breast cancer in Brazilian patients

BackgroundBreast cancer is the leading cause of cancer death among women worldwide. Studies about the genomic landscape of metastatic breast cancer (MBC) have predominantly originated from developed nations. There are still limited data on the molecular epidemiology of MBC in low- and middle-income...

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Main Authors: Tomás Reinert, Fernanda Orpinelli do Rego, Matheus Costa e Silva, Amanda Muniz Rodrigues, Fernanda Christtanini Koyama, Aline Coelho Gonçalves, Maiane Maria Pauletto, Leandro Jonata de Carvalho Oliveira, Cristiano Augusto Andrade de Resende, Luciana Castro Garcia Landeiro, Carlos Henrique Barrios, Max Senna Mano, Rodrigo Dienstmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Oncology
Subjects:
breast neoplasm
estrogen receptor
genomic landscape
PI3K/Akt pathway
targeted therapies
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1372947/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1372947/full

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