Impact of Superantigen-Producing Bacteria on T Cells from Tonsillar Hyperplasia

Impact of Superantigen-Producing Bacteria on T Cells from Tonsillar Hyperplasia

<i>Staphylococcus aureus</i> and Group A Streptococcus (GAS) are common occupants of the tonsils and many strains produce potent exotoxins (mitogens) that directly target T cells, which could be a driver for tonsillar hyperplasia. Tonsil tissues from 41 patients were tested for these bac...

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Bibliographic Details
Main Authors: Fiona J Radcliff, Sharon Waldvogel-Thurlow, Fiona Clow, Murali Mahadevan, James Johnston, Gen Li, Thomas Proft, Richard G Douglas, John D Fraser
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Pathogens
Subjects:
superantigen
<i>Staphylococcus aureus</i>
<i>Streptococcus pyogenes</i>
Group A Streptococcus
TCR Vβ
mucosal-associated invariant T cells
recurrent tonsillitis
obstructive sleep apnea
tonsillar hyperplasia
Online Access:https://www.mdpi.com/2076-0817/8/3/90

Internet

https://www.mdpi.com/2076-0817/8/3/90

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