Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases

Background Tumors avoid destruction by cytotoxic T cells (CTL) and natural killer (NK) cells by downregulation of classical human leukocyte antigens (HLA) and overexpression of non-classical HLA. This is the first study to investigate HLA expression in relation to histology (squamous cell carcinoma...

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Bibliographic Details
Main Authors: Sanne Samuels, Tanja D. de Gruijl, Debbie M. Ferns, A. Marijne Heeren, Maaike C. G. Bleeker, Gemma G. Kenter, Ekaterina S. Jordanova
Format: Article
Language:English
Published: BMJ Publishing Group 2016-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/4/1/78.full