Modified gold nanoparticle colorimetric probe-based biosensor coupled with allele-specific PCR for rapid detection of G944C mutation associated with isoniazid resistance

Modified gold nanoparticle colorimetric probe-based biosensor coupled with allele-specific PCR for rapid detection of G944C mutation associated with isoniazid resistance

The emergence of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB) makes tuberculosis (TB) difficult to control and treat. Therefore, rapid and reliable detection of MDR-TB within the community plays a significant role. The aim of this study was to investigate the use of modified...

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Bibliographic Details
Main Authors: Sara Kooti, Ramin Abiri, Sepide Kadivarian, Saeed Khazayel, Parviz Mohajeri, Sara Atashi, Farideh Yari, Hossein Ahmadpour, Amirhooshang Alvandi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Sensing and Bio-Sensing Research
Subjects:
Biosensor
Allele-specific PCR
G944C mutation
Isoniazid resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2214180422000721

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http://www.sciencedirect.com/science/article/pii/S2214180422000721

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