VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer

VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer

Abstract Androgen deprivation therapy (ADT) is a standard therapy for prostate cancer (PCa). Though disseminated disease is initially sensitive to ADT, an important fraction of the patients progresses to castration-resistant prostate cancer (CRPC). For this reason, the identification of novel effect...

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Bibliographic Details
Main Authors: Rydell Alvarez-Arzola, Nicoló Bancaro, Ping Lai, Giuseppe Attanasio, Laura Pellegrini, Martina Troiani, Manuel Colucci, Simone Mosole, Emiliano Pasquini, Andrea Alimonti, Circe Mesa
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cell Communication and Signaling
Subjects:
Macrophages
VSSP
Prostate cancer
Adoptive transfer
Online Access:https://doi.org/10.1186/s12964-023-01095-3

Internet

https://doi.org/10.1186/s12964-023-01095-3

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