Determining appropriate input excitation for model identification of a continuous bio-process

Determining appropriate input excitation for model identification of a continuous bio-process

This manuscript addresses the problem of determining input excitation for data driven model identification appropriate for cell culture bio-processes in general, and for an industrial bioreactor used for the production of monoclonal antibodies, in particular. The design space is set up to give us th...

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Bibliographic Details
Main Authors: Samardeep Sarna, Nikesh Patel, Brandon Corbett, Chris McCready, Prashant Mhaskar
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Digital Chemical Engineering
Subjects:
Data driven modelling of bio processes
Subspace identification
Data driven model identification
Intensified design of experiments
Chinese Hamster Ovary (CHO) cells
Online Access:http://www.sciencedirect.com/science/article/pii/S277250812200062X

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http://www.sciencedirect.com/science/article/pii/S277250812200062X

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