Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation and anti-obesity effects

Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation and anti-obesity effects

Abstract Background Exercise training is well established as the most effective way to enhance muscle performance and muscle building. The composition of skeletal muscle fiber type affects systemic energy expenditures, and perturbations in metabolic homeostasis contribute to the onset of obesity and...

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Bibliographic Details
Main Authors: Yajuan Li, Yaohua Zhang, Qingsong Hu, Sergey D. Egranov, Zhen Xing, Zhao Zhang, Ke Liang, Youqiong Ye, Yinghong Pan, Sujash S. Chatterjee, Brandon Mistretta, Tina K. Nguyen, David H. Hawke, Preethi H. Gunaratne, Mien-Chie Hung, Leng Han, Liuqing Yang, Chunru Lin
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Medicine
Subjects:
Long noncoding RNA
H19
Skeletal muscle
Obesity
RNA therapy
Dystrophin
Online Access:https://doi.org/10.1186/s13073-021-00937-4

Internet

https://doi.org/10.1186/s13073-021-00937-4

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