The Presence of the Temporal Horn Exacerbates the Vulnerability of Hippocampus During Head Impacts

The Presence of the Temporal Horn Exacerbates the Vulnerability of Hippocampus During Head Impacts

Hippocampal injury is common in traumatic brain injury (TBI) patients, but the underlying pathogenesis remains elusive. In this study, we hypothesize that the presence of the adjacent fluid-containing temporal horn exacerbates the biomechanical vulnerability of the hippocampus. Two finite element mo...

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Bibliographic Details
Main Authors: Zhou Zhou, Xiaogai Li, August G. Domel, Emily L. Dennis, Marios Georgiadis, Yuzhe Liu, Samuel J. Raymond, Gerald Grant, Svein Kleiven, David Camarillo, Michael Zeineh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
hippocampal injury
temporal horn
brain-ventricle interface
fluid-structure interaction
finite element analysis
traumatic brain injury
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.754344/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.754344/full

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