History of tuberculosis disease is associated with genetic regulatory variation in Peruvians.

History of tuberculosis disease is associated with genetic regulatory variation in Peruvians.

A quarter of humanity is estimated to have been exposed to Mycobacterium tuberculosis (Mtb) with a 5-10% risk of developing tuberculosis (TB) disease. Variability in responses to Mtb infection could be due to host or pathogen heterogeneity. Here, we focused on host genetic variation in a Peruvian po...

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Bibliographic Details
Main Authors: Victor E Nieto-Caballero, Josephine F Reijneveld, Angel Ruvalcaba, Gabriel Innocenzi, Nalin Abeydeera, Samira Asgari, Kattya Lopez, Sarah K Iwany, Yang Luo, Aparna Nathan, Daniela Fernandez-Salinas, Marcos Chiñas, Chuan-Chin Huang, Zibiao Zhang, Segundo R León, Roger I Calderon, Leonid Lecca, Jonathan M Budzik, Megan Murray, Ildiko Van Rhijn, Soumya Raychaudhuri, D Branch Moody, Sara Suliman, Maria Gutierrez-Arcelus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011313

Internet

https://doi.org/10.1371/journal.pgen.1011313

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