New Bicyclic Pyridine-Based Hybrids Linked to the 1,2,3-Triazole Unit: Synthesis via Click Reaction and Evaluation of Neurotropic Activity and Molecular Docking

New Bicyclic Pyridine-Based Hybrids Linked to the 1,2,3-Triazole Unit: Synthesis via Click Reaction and Evaluation of Neurotropic Activity and Molecular Docking

The synthesis of new original bicyclic pyridine-based hybrids linked to the 1,2,3-triazole unit was described via a click reaction. The anticonvulsant activity and some psychotropic properties of the new compounds were evaluated. The biological assays demonstrated that some of the studied compounds...

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Bibliographic Details
Main Authors: Samvel N. Sirakanyan, Domenico Spinelli, Anthi Petrou, Athina Geronikaki, Victor G. Kartsev, Elmira K. Hakobyan, Hasmik A. Yegoryan, Luca Zuppiroli, Riccardo Zuppiroli, Armen G. Ayvazyan, Ruzanna G. Paronikyan, Tatevik A. Arakelyan, Anush A. Hovakimyan
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
condensed pyridines
hybrids
click reaction
neurotropic activity
Online Access:https://www.mdpi.com/1420-3049/28/3/921

Internet

https://www.mdpi.com/1420-3049/28/3/921

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