Molecular and hematological studies in a cohort of beta zero South East Asia deletion (β°-thal SEA) from Malaysian perspective

Molecular and hematological studies in a cohort of beta zero South East Asia deletion (β°-thal SEA) from Malaysian perspective

AbstractWe report the haematological parameters and molecular characterization of beta zero (β°) South East Asia (SEA) deletion in the HBB gene cluster with unusually high levels of Hb F compared to a classical heterozygous beta zero (β°)-thalassaemia.MethodsRetrospective study on 17 cases of (β°) S...

Full description

Bibliographic Details
Main Authors: Norafiza Mohd Yasin, Faidatul Syazlin Abdul Hamid, Syahzuwan Hassan, Aziee Sudin, Haiyuni Yassim, Ermi Neiza Mohd Sahid, Yuslina Mat Yusoff, Ezalia Esa, Mohamed Saleem
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pediatrics
Subjects:
beta-thalassaemia
HPFH
deltabeta thalassaemia
deletional mutation
β°-thal SEA
β° deletion
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.974496/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2022.974496/full

Similar Items