Cortical microstructure in primary progressive aphasia: a multicenter study

Cortical microstructure in primary progressive aphasia: a multicenter study

Abstract Background Cortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive biomarker that might antedate macroscopic cortical...

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Main Authors: Ignacio Illán-Gala, Victor Montal, Sergi Borrego-Écija, Maria Luisa Mandelli, Neus Falgàs, Ariane E. Welch, Jordi Pegueroles, Miguel Santos-Santos, Alexandre Bejanin, Daniel Alcolea, Oriol Dols-Icardo, Olivia Belbin, Mª. Belén Sánchez-Saudinós, Nuria Bargalló, Sofía González-Ortiz, Albert Lladó, Rafael Blesa, Bradford C. Dickerson, Howard J. Rosen, Bruce L. Miller, Alberto Lleó, Maria Luisa Gorno-Tempini, Raquel Sánchez-Valle, Juan Fortea
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Diffusion
Magnetic resonance
Primary progressive aphasia
Alzheimer’s disease
Frontotemporal lobar degeneration
Online Access:https://doi.org/10.1186/s13195-022-00974-0

Internet

https://doi.org/10.1186/s13195-022-00974-0

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