Monitoring of Cardiorespiratory Parameters in Rats—Validation Based on Pharmacological Stimulation

The methods used in preclinical studies should minimize the suffering and the number of animals but still provide precise and consistent results enabling the introduction of drug candidates into the phase of clinical trials. Thus, we aimed to develop a method allowing us to perform preliminary safet...

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Bibliographic Details
Main Authors: Joanna Miklosz, Bartlomiej Kalaska, Stanislaw Zajaczkowski, Dariusz Pawlak, Andrzej Mogielnicki
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/12/1223