Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine

Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine

Background: Azathioprine is frequently used in severe eczema. It is converted in the liver into active metabolites, including 6-thioguanine nucleotide (6-TGN) and methylated 6-methylmercaptopurine (6-MMP). In the past, the therapeutic potential of azathioprine may have not been fully utilized. Recen...

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Bibliographic Details
Main Authors: F. M. Garritsen, J. van der Schaft, C. A. F. Bruijnzeel-Koomen, R. H. van Schaik, M. de Graaf, M. P. H. van den Broek, M. S. de Bruin-Weller
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Journal of Dermatological Treatment
Subjects:
atopic dermatitis
azathioprine
metabolites
therapeutic drug monitoring
Online Access:http://dx.doi.org/10.1080/09546634.2017.1373738

Internet

http://dx.doi.org/10.1080/09546634.2017.1373738

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