Inflammation-associated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor

In a prospective, longitudinal study, we investigated the association between decreased ADAMTS13 activity and impaired hemostasis, as well as organ dysfunctions in patients with systemic inflammation due to extracorporeal cardiopulmonary circuit or with severe sepsis. Similar to negative acute phase...

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Bibliographic Details
Main Authors: Clemens L. Bockmeyer, Ralf A. Claus, Ulrich Budde, Karim Kentouche, Reinhard Schneppenheim, Wolfgang Lösche, Konrad Reinhart, Frank M. Brunkhorst
Format: Article
Language:English
Published: Ferrata Storti Foundation 2008-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/4699