Loss of monoacylglycerol O-acyltransferase 2 can be compensated for by diacylglycerol O-acyltransferases 1 and 2 resulting in a negligible influence on mammary cancer development found in a mouse model and verified in human tissues

Loss of monoacylglycerol O-acyltransferase 2 can be compensated for by diacylglycerol O-acyltransferases 1 and 2 resulting in a negligible influence on mammary cancer development found in a mouse model and verified in human tissues

Background: Dietary fat absorption involves the re-esterification of digested triacylglycerol in the enterocytes, it is a biological process catalyzed by monoacylglycerol O-acyltransferase 2 (MOGAT2, aka MGAT2), which is highly expressed in the small intestine. A previous study showed that the loss...

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Bibliographic Details
Main Authors: Mei Yan, Wang Jing, Lu Jia-Bin, Lu Guan-Ming, Peng Li-Xia, Lang Yan-Hong, Zheng Li-Sheng, Huang Bi-Jun, Shi Yan-Xia, Qian Chao-Nan
Format: Article
Language:English
Published: EDP Sciences 2023-01-01
Series:Visualized Cancer Medicine
Subjects:
mogat2 depletion
mmtv-pymt
mammary tumor
dgat1
dgat2
Online Access:https://vcm.edpsciences.org/articles/vcm/full_html/2023/01/vcm20230004/vcm20230004.html

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https://vcm.edpsciences.org/articles/vcm/full_html/2023/01/vcm20230004/vcm20230004.html

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