Retinoic Acid Potentiates the Therapeutic Efficiency of Bone Marrow-Derived Mesenchymal Stem Cells (BM-MSCs) against Cisplatin-Induced Hepatotoxicity in Rats

Retinoic Acid Potentiates the Therapeutic Efficiency of Bone Marrow-Derived Mesenchymal Stem Cells (BM-MSCs) against Cisplatin-Induced Hepatotoxicity in Rats

(1) Background: Hepatotoxicity is a common health problem, and oxidative stress plays a crucial role in its underlying mechanisms. We inspected the possible effect of retinoic acid (RA) in the potentiation of hepatoprotective effect of bone marrow mesenchymal stem cells (BM-MSCs) against Cisplatin (...

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Bibliographic Details
Main Authors: Maha M. Azzam, Abdelaziz M. Hussein, Basma H. Marghani, Nashwa M. Barakat, Mohsen M. M. Khedr, Nabil Abu Heakel
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Scientia Pharmaceutica
Subjects:
cisplatin hepatotoxicity
BM-MSCs
retinoic acid
oxidative stress
NADPH oxidase
apoptosis
Online Access:https://www.mdpi.com/2218-0532/90/4/58

Internet

https://www.mdpi.com/2218-0532/90/4/58

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