Human papillomavirus infection can alter the level of tumour stemness and T cell infiltration in patients with head and neck squamous cell carcinoma

Human papillomavirus infection can alter the level of tumour stemness and T cell infiltration in patients with head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) usually has a poor prognosis and is associated with a high mortality rate. Its etiology is mainly the result from long-term exposure to either alcohol, tobacco or human papillomavirus (HPV) infection or a combination of these insults. However, HNSCC pati...

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Bibliographic Details
Main Authors: Lingzhang Meng, Heming Lu, Yueyong Li, Jingjie Zhao, Siyuan He, Zechen Wang, Jiajia Shen, Huixian Huang, Jinru Xiao, Suren Rao Sooranna, Jian Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
human papillomavirus
single cell transcriptomic
head and neck squamous cell carcinoma
tumour stemness
tumour infiltrating immune cells
immune checkpoint genes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013542/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013542/full

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