Differential Expression of Lonp1 Isoforms in Cancer Cells

Lonp1 is a mitochondrial protease that degrades oxidized and damaged proteins, assists protein folding, and contributes to the maintenance of mitochondrial DNA. A higher expression of LonP1 has been associated with higher tumour aggressiveness. Besides the full-length isoform (ISO1), we identified t...

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Bibliographic Details
Main Authors: Giada Zanini, Valentina Selleri, Anna De Gaetano, Lara Gibellini, Mara Malerba, Anna Vittoria Mattioli, Milena Nasi, Nadezda Apostolova, Marcello Pinti
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/23/3940