MicroRNA-205 mediates endothelial progenitor functions in distraction osteogenesis by targeting the transcription regulator NOTCH2

MicroRNA-205 mediates endothelial progenitor functions in distraction osteogenesis by targeting the transcription regulator NOTCH2

Abstract Background Distraction osteogenesis (DO) is a highly efficacious form of reconstructive bone regeneration, but its clinical utility is limited by the prolonged period required for bone consolidation to occur. Understanding the mechanistic basis for DO and shortening this consolidation phase...

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Bibliographic Details
Main Authors: Weidong Jiang, Peiqi Zhu, Tao Zhang, Fengchun Liao, Yangyang Yu, Yan Liu, Huijuan Shen, Zhenchen Zhao, Xuanping Huang, Nuo Zhou
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Distraction osteogenesis
microRNA-205
NOTCH2
Endothelial colony-forming cells
Bone regeneration
Angiogenesis
Online Access:https://doi.org/10.1186/s13287-021-02150-x

Internet

https://doi.org/10.1186/s13287-021-02150-x

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