Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca2+ signaling and IKCa activation

Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca2+ signaling and IKCa activation

Abstract Although absorption of di‐ and tripeptides into intestinal epithelial cells occurs via the peptide transporter 1 (PEPT1, also called solute carrier family 15 member 1 (SLC15A1)), the detailed regulatory mechanisms are not fully understood. We examined: (a) whether dipeptide absorption in vi...

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Bibliographic Details
Main Authors: Jingyu Xu, Andre Zeug, Brigitte Riederer, Sunil Yeruva, Oliver Griesbeck, Hannelore Daniel, Biguang Tuo, Evgeni Ponimaskin, Hui Dong, Ursula Seidler
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Physiological Reports
Subjects:
calcium sensing receptor
dipeptide absorption
intestine
intracellular calcium signaling
peptide transporter 1
Online Access:https://doi.org/10.14814/phy2.14337

Internet

https://doi.org/10.14814/phy2.14337

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