Elucidating Cuproptosis-Associated Genes in the Progression from Nash to HCC Using Bulk and Single-Cell RNA Sequencing Analyses and Experimental Validation

Elucidating Cuproptosis-Associated Genes in the Progression from Nash to HCC Using Bulk and Single-Cell RNA Sequencing Analyses and Experimental Validation

<i>Background and Objectives</i>: Non-alcoholic steatohepatitis (NASH) is a significant risk factor for hepatocellular carcinoma (HCC) development. Timely treatment during the NASH stage is essential to minimize the possibility of disease progression to HCC. Cuproptosis is a newly identi...

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Bibliographic Details
Main Authors: Zizuo Zhao, Tiankuo Luan, Jingyuan Wan, Hui Du, Jun Hu, Hao Liu, Xia Gong, Ge Kuang, Bin Wang
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Medicina
Subjects:
FDX1
NASH to HCC
immune landscape
cuproptosis
Online Access:https://www.mdpi.com/1648-9144/59/9/1639

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https://www.mdpi.com/1648-9144/59/9/1639

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