Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression

Abstract Backgrounds and aims As a central event during liver fibrosis, hepatic stellate cells (HSC) have been thought to be a potential therapeutic target for liver fibrosis. Previous studies have shown that runt‐related transcription factor 2 (Runx2) is associated with the development of non‐alcoh...

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Bibliographic Details
Main Authors: Li Zhong, Jinqiu Zhao, Lu Huang, Yi Liu, Xiaoxiao Pang, Ke Zhan, Shan Li, Qian Xue, Xiaoli Pan, Liang Deng
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1316