What are activated and reactive glia and what is their role in neurodegeneration?

In injury and disease, microglia and astrocytes - two major non-neuronal cell types in the central nervous system (CNS) - undergo morphological, transcriptional, and functional changes, which can underlie pathogenesis and dysfunction of the CNS. Microglia, the brain's tissue resident parenchyma...

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Bibliographic Details
Main Authors: Mariko L. Bennett, Angela N. Viaene
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304472