What are activated and reactive glia and what is their role in neurodegeneration?
In injury and disease, microglia and astrocytes - two major non-neuronal cell types in the central nervous system (CNS) - undergo morphological, transcriptional, and functional changes, which can underlie pathogenesis and dysfunction of the CNS. Microglia, the brain's tissue resident parenchyma...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996120304472 |