Translocator protein activates autophagy in diabetic neuropathic pain rats via regulation of the Keap1/Nrf2/HO-1 signaling

Translocator protein activates autophagy in diabetic neuropathic pain rats via regulation of the Keap1/Nrf2/HO-1 signaling

Objective·To study the effects of translocator protein (TSPO) agonist Ro5-4864 on autophagy and Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid-derived-2-like 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling in diabetic neuropathic pain (DNP) rats.Methods·Type 2 diabetic rats were est...

Full description

Bibliographic Details
Main Authors: GAO Nan, HAO Gem, MA Bingjie, JIN Tian, MA Ke, LIU Xiaoming
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2023-08-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:
translocator protein (tspo)
neuropathic pain (np)
diabetes
autophagy
kelch-like ech-associated protein 1 (keap1)/nuclear factor erythroid-derived-2-like 2 (nrf2)/heme oxygenase-1 (ho-1) signaling (keap1/nrf2/ho-1 signaling)
Online Access:https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-8-988.shtml

Internet

https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-8-988.shtml

Similar Items