Investigation of the Role of the TRPA1 Ion Channel in Conveying the Effect of Dimethyl Trisulfide on Vascular and Histological Changes in Serum-Transfer Arthritis

Investigation of the Role of the TRPA1 Ion Channel in Conveying the Effect of Dimethyl Trisulfide on Vascular and Histological Changes in Serum-Transfer Arthritis

Rheumatoid arthritis (RA) is one of the most prevalent autoimmune diseases. Its therapy is often challenging, even in the era of biologicals. Previously, we observed the anti-inflammatory effects of garlic-derived organic polysulfide dimethyl trisulfide (DMTS). Some of these effects were mediated by...

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Bibliographic Details
Main Authors: István Z. Bátai, Ágnes Dombi, Éva Borbély, Ádám Fehér, Ferenc Papp, Zoltan Varga, Attila Mócsai, Zsuzsanna Helyes, Erika Pintér, Gábor Pozsgai
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
dimethyl trisulfide
K/BxN serum-transfer arthritis
TRPA1 ion channel
plasma extravasation
fibroblast-like synoviocyte
cartilage destruction
Online Access:https://www.mdpi.com/1424-8247/15/6/671

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https://www.mdpi.com/1424-8247/15/6/671

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