The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms

The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms

Identifying ancestry-specific molecular profiles of late-onset Alzheimer's Disease (LOAD) in brain tissue is crucial to understand novel mechanisms and develop effective interventions in non-European, high-risk populations. We performed gene differential expression (DE) and consensus network-ba...

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Bibliographic Details
Main Authors: Daniel Felsky, Ismael Santa-Maria, Mehmet Ilyas Cosacak, Leon French, Julie A. Schneider, David A. Bennett, Philip L. De Jager, Caghan Kizil, Giuseppe Tosto
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Neurobiology of Disease
Subjects:
Caribbean-Hispanic
Brain gene expression
Alzheimer's disease
Bulk tissue
Single cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122003308

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http://www.sciencedirect.com/science/article/pii/S0969996122003308

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