Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21

Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21

Methionine restriction (MR) extends lifespan and delays the onset of aging-associated pathologies. However, the effect of MR on age-related cognitive decline remains unclear. Here, we find that a 3-month MR ameliorates working memory, short-term memory, and spatial memory in 15-month-old and 18-mont...

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Bibliographic Details
Main Authors: Bo Ren, Luanfeng Wang, Lin Shi, Xin Jin, Yan Liu, Rui Hai Liu, Fei Yin, Enrique Cadenas, Xiaoshuang Dai, Zhigang Liu, Xuebo Liu
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Methionine restriction
Aging
Cognitive decline
Fibroblast growth factor 21
Nrf2
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000884

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http://www.sciencedirect.com/science/article/pii/S2213231721000884

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