Combination therapy with saxagliptin and vitamin D for the preservation of β-cell function in adult-onset type 1 diabetes: a multi-center, randomized, controlled trial

Abstract Disease modifying therapies aiming to preserve β-cell function in patients with adult-onset autoimmune type 1 diabetes are lacking. Here, we conducted a multi-centre, randomized, controlled trial to assess the β-cell preservation effects of saxagliptin alone and saxagliptin combined with vi...

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Bibliographic Details
Main Authors: Xiang Yan, Xia Li, Bingwen Liu, Jiaqi Huang, Yufei Xiang, Yuhang Hu, Xiaohan Tang, Ziwei Zhang, Gan Huang, Zhiguo Xie, Houde Zhou, Zhenqi Liu, Xiangbing Wang, Richard David Leslie, Zhiguang Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01369-9