Clinical features, laboratory and molecular findings of children with leukocyte adhesion deficiency type-III from a single center in India

Clinical features, laboratory and molecular findings of children with leukocyte adhesion deficiency type-III from a single center in India

Leukocyte adhesion deficiency (LAD) Type-III is caused by homozygous mutations in FERMT3 causing Kindlin-3 deficiency. Here we describe three children with molecularly proven LAD-III presenting with neonatal onset mucocutaneous bleeding, infections and persistent neutrophilic leukocytosis. CD18 and...

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Bibliographic Details
Main Authors: Akshaya Chougule, Prasad Taur, Vaishnavi V. Iyengar, Vijaya Gowri, Bipin P. Kulkarni, Manisha R. Madkaikar, Minnie Bodhanwala, Mukesh M. Desai
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Pediatric Hematology Oncology Journal
Subjects:
Leukocytosis
Bleeding tendencies
Primary immunodeficiency
Leukocyte adhesion deficiency type-III
Online Access:http://www.sciencedirect.com/science/article/pii/S2468124522005216

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http://www.sciencedirect.com/science/article/pii/S2468124522005216

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