DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study

DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study

(4E)-7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) derived from A. officinarum Hance has been reported to exert anti-inflammatory and anti-insulin resistance (IR) effects. We explored the molecular mechanism of DPHB ameliorating IR through network pharmacological prediction and in vit...

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Bibliographic Details
Main Authors: Xiangyi Li, Huan Wen, Yuxin Zhang, Aixia Liu, Xuguang Zhang, Minghai Fu, Yipeng Pan, Jian Xu, Junqing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
network pharmacology
molecular docking
(4E)-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one
Alpinia officinarum Hance
insulin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.956812/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.956812/full

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