Whole exome sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes

Whole exome sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes

Abstract Whole Exome Sequencing (WES) studies provide important insights into the genetic architecture of serious mental illness (SMI). Genes that are central to the shared biology of SMIs may be identified by WES in families with multiple affected individuals with diverse SMI (F-SMI). We performed...

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Main Authors: Suhas Ganesh, Alekhya Vemula, Samsiddhi Bhattacharjee, Kezia Mathew, Dhruva Ithal, Karthick Navin, Ravi Kumar Nadella, Biju Viswanath, Patrick F. Sullivan, The ADBS Consortium, Sanjeev Jain, Meera Purushottam
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25664-7

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https://doi.org/10.1038/s41598-022-25664-7

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