Multiscalar cellular automaton simulates in-vivo tumour-stroma patterns calibrated from in-vitro assay data

Multiscalar cellular automaton simulates in-vivo tumour-stroma patterns calibrated from in-vitro assay data

Abstract Background The tumour stroma -or tumour microenvironment- is an important constituent of solid cancers and it is thought to be one of the main obstacles to quantitative translation of drug activity between the preclinical and clinical phases of drug development. The tumour-stroma relationsh...

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Bibliographic Details
Main Authors: J. A. Delgado-SanMartin, J. I. Hare, E. J. Davies, J. W. T. Yates
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Cancer
Stroma
Cellular automaton
Oxygen
Hypoxia
Immunohistochemistry
Online Access:http://link.springer.com/article/10.1186/s12911-017-0461-1

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http://link.springer.com/article/10.1186/s12911-017-0461-1

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