Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression

<p>Abstract</p> <p>Background</p> <p>Less than 30% of malignant gliomas respond to adjuvant chemotherapy. Here, we have asked whether variations in the constitutive expression of early-growth response factor 1 (EGR-1) predicted acute cytotoxicity and clonogenic cell dea...

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Bibliographic Details
Main Authors: Ponti Donatella, Arcella Antonietta, Miscusi Massimo, Lombari Vincenza, Fabbiano Cinzia, Porcellini Antonio, Calogero Antonella, Ragona Giuseppe
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/11/1/5