Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

Abstract Background Acyl hydrazones are an important class of heterocyclic compounds promising pharmacological characteristics. Malaria is a life-threatening mosquito-borne blood disease caused by a plasmodium parasite. In some places, malaria can be treated and controlled with early diagnosis. Howe...

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Bibliographic Details
Main Authors: Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Jayant Sindhu, Vineeta Singh, Baljeet Singh Saharan
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Chemistry Central Journal
Subjects:
Antimalarial
DHP
Pyrazole
Conformational studies
Plasmodium falciparum
Falcipain-2
Online Access:http://link.springer.com/article/10.1186/s13065-017-0344-7

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http://link.springer.com/article/10.1186/s13065-017-0344-7

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