Cytoprotective organoselenium compounds for oligodendrocytes

Cytoprotective organoselenium compounds for oligodendrocytes

Herein we report the synthesis of peptide-like and tetrazole-based organoselenium compounds via Ugi and Ugi-azide reactions, respectively. The organoselenium compounds' intrinsic cytoprotective and antioxidant capacities were evaluated in 158 N and 158JP murine oligodendrocytes. Furthermore, th...

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Bibliographic Details
Main Authors: Saad Shaaban, Amira Zarrouk, Dominique Vervandier-Fasseur, Yasair S.Al-Faiyz, Hany El-Sawy, Ismail Althagafi, Pierre Andreoletti, Mustapha Cherkaoui-Malki
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Arabian Journal of Chemistry
Subjects:
Organoselenium
Ugi reaction
Tetrazole
Antioxidant
Oligodendrocytes
Cytoprotective
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221000666

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http://www.sciencedirect.com/science/article/pii/S1878535221000666

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