Inhibition of experimental autoimmune uveitis by intravitreal AAV-Equine-IL10 gene therapy.

Equine recurrent uveitis (ERU) is a spontaneous, painful, and vision threatening disease affecting up to 25% of equine populations worldwide. Current treatments of ERU are non-specific and have many side effects which limits them to short-term use. In order to develop an effective therapy for ERU, w...

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Bibliographic Details
Main Authors: Elizabeth Crabtree, Katy Uribe, Sara M Smith, Darby Roberts, Jacklyn H Salmon, Jacquelyn J Bower, Liujiang Song, Prabhakar Bastola, Matthew L Hirsch, Brian C Gilger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0270972