Ex Vivo Model to Assess the Exposure of Patients to Plasticizers from Medical Devices during Pre-CAR-T Cells’ Apheresis

Background: The treatment of relapsed or refractory leukemia remains a major problem. Among the new therapeutic approaches, the use of modified T lymphocytes, called chimeric antigen receptor T cells (CAR-T cells), seems promising. The first step of their preparation is leukapheresis, which involves...

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Bibliographic Details
Main Authors: Raphaëlle Lautraite, Lise Bernard, Pascale Halle, Philip Chennell, Yoann Le Basle, Justyna Kanold, Valérie Sautou
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/10/2/79