Characterization of BV6-Induced Sensitization to the NK Cell Killing of Pediatric Rhabdomyosarcoma Spheroids

Characterization of BV6-Induced Sensitization to the NK Cell Killing of Pediatric Rhabdomyosarcoma Spheroids

Although the overall survival in pediatric rhabdomyosarcoma (RMS) has increased over the last decades, the most aggressive subtype of alveolar RMS is in dire need of novel treatment strategies. RMS cells evade cell death induction and immune control by increasing the expression of inhibitors of apop...

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Bibliographic Details
Main Authors: Vinzenz Särchen, Lisa Marie Reindl, Sara Wiedemann, Senthan Shanmugalingam, Thomas Bukur, Julia Becker, Martin Suchan, Evelyn Ullrich, Meike Vogler
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
NK cells
Smac mimetic
BV6
cell death
rhabdomyosarcoma
tumor spheroids
Online Access:https://www.mdpi.com/2073-4409/12/6/906

Internet

https://www.mdpi.com/2073-4409/12/6/906

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