Dynamics of Ring-Cleavage Reactions in Temozolomide Induced by Low-Energy Electron Attachment

Dynamics of Ring-Cleavage Reactions in Temozolomide Induced by Low-Energy Electron Attachment

We have used a crossed electron molecular beam setup to investigate the behavior of the anticancer drug temozolomide (TMZ) upon the attachment of low-energy electrons (0–14 eV) in the gas phase. Upon a single electron attachment, eight anionic fragments are observed, the most intense being an anion...

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Bibliographic Details
Main Authors: Eugene Arthur-Baidoo, Farhad Izadi, Carlos Guerra, Gustavo Garcia, Milan Ončák, Stephan Denifl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Physics
Subjects:
temozolomide
electron attachment
imidazole ring
gas phase
ring cleavage
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.880689/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2022.880689/full

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