Hydrogel platform facilitating astrocytic differentiation through cell mechanosensing and YAP-mediated transcription

Hydrogel platform facilitating astrocytic differentiation through cell mechanosensing and YAP-mediated transcription

Astrocytes are multifunctional glial cells that are essential for brain functioning. Most existing methods to induce astrocytes from stem cells are inefficient, requiring couples of weeks. Here, we designed an alginate hydrogel-based method to realize high-efficiency astrocytic differentiation from...

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Bibliographic Details
Main Authors: Zhongqian Liu, Shijie Mao, Yubin Hu, Feng Liu, Xiaowei Shao
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Materials Today Bio
Subjects:
Hydrogel
Neural stem cell
Astrocyte
Mechanobiology
YAP
Ca2+ channel
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423001953

Internet

http://www.sciencedirect.com/science/article/pii/S2590006423001953

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