Elevating the potential of CAR-T cell therapy in solid tumors: exploiting biomaterials-based delivery techniques

Elevating the potential of CAR-T cell therapy in solid tumors: exploiting biomaterials-based delivery techniques

Chimeric antigen receptor (CAR) T cells exhibit promising progress in addressing hematologic malignancies. However, CAR-T therapy for solid tumors remains limited, with no FDA-approved CAR-T products available for clinical use at present. Primary reasons include insufficient infiltration, accumulati...

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Bibliographic Details
Main Authors: Yuxiang Tang, Xiaoyu Yang, Hang Hu, Huiwen Jiang, Wei Xiong, Heng Mei, Yu Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
chimeric antigen receptor-T
biomaterials
solid tumor
immunotherapy
nanobackpack
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1320807/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1320807/full

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