Optimised Non-Coding Regions of mRNA SARS-CoV-2 Vaccine CV2CoV Improves Homologous and Heterologous Neutralising Antibody Responses

More than two years after the emergence of SARS-CoV-2, 33 COVID-19 vaccines, based on different platforms, have been approved in 197 countries. Novel variants that are less efficiently neutralised by antibodies raised against ancestral SARS-CoV-2 are circulating, highlighting the need to adapt vacci...

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Bibliographic Details
Main Authors: Nicole Roth, Jacob Schön, Donata Hoffmann, Moritz Thran, Andreas Thess, Stefan O. Mueller, Benjamin Petsch, Susanne Rauch
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/8/1251