CerS1 but Not CerS5 Gene Silencing, Improves Insulin Sensitivity and Glucose Uptake in Skeletal Muscle

CerS1 but Not CerS5 Gene Silencing, Improves Insulin Sensitivity and Glucose Uptake in Skeletal Muscle

Skeletal muscle is perceived as a major tissue in glucose and lipid metabolism. High fat diet (HFD) lead to the accumulation of intramuscular lipids, including: long chain acyl-CoA, diacylglycerols, and ceramides. Ceramides are considered to be one of the most important lipid groups in the generatio...

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Bibliographic Details
Main Authors: Agnieszka U. Błachnio-Zabielska, Kamila Roszczyc-Owsiejczuk, Monika Imierska, Karolina Pogodzińska, Paweł Rogalski, Jarosław Daniluk, Piotr Zabielski
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
skeletal muscle
insulin resistance
ceramides
gene silencing
mass spectrometry
Online Access:https://www.mdpi.com/2073-4409/11/2/206

Internet

https://www.mdpi.com/2073-4409/11/2/206

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