A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

Abstract Over the last decade, the field of cancer metabolism has mainly focused on studying the role of tumorigenic metabolic rewiring in supporting cancer proliferation. Here, we perform the first genome‐scale computational study of the metabolic underpinnings of cancer migration. We build genome‐...

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Bibliographic Details
Main Authors: Keren Yizhak, Sylvia E Le Dévédec, Vasiliki Maria Rogkoti, Franziska Baenke, Vincent C deBoer, Christian Frezza, Almut Schulze, Bob van deWater, Eytan Ruppin
Format: Article
Language:English
Published: Springer Nature 2014-08-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20134993