A mechanobiological computer optimization framework to design scaffolds to enhance bone regeneration

The treatment of large bone defects is a clinical challenge. 3D printed scaffolds are a promising treatment option for such critical-size defects. However, the design of scaffolds to treat such defects is challenging due to the large number of variables impacting bone regeneration; material stiffnes...

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Bibliographic Details
Main Authors: Camille Perier-Metz, Georg N. Duda, Sara Checa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.980727/full