Activated B-Cells enhance epitope spreading to support successful cancer immunotherapy

Activated B-Cells enhance epitope spreading to support successful cancer immunotherapy

Immune checkpoint therapies (ICT) have transformed the treatment of cancer over the past decade. However, many patients do not respond or suffer relapses. Successful immunotherapy requires epitope spreading, but the slow or inefficient induction of functional antitumoral immunity delays the benefit...

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Bibliographic Details
Main Authors: Guillaume Kellermann, Nicolas Leulliot, Julien Cherfils-Vicini, Magali Blaud, Patrick Brest
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
B-cell
tolerance
immunotherapy
epitope spreading
RNA binding protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382236/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382236/full

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