PLUS-IS-LESS project: Procalcitonin and Lung UltraSonography-based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments: study protocol for a pragmatic stepped-wedge cluster-randomized trial

PLUS-IS-LESS project: Procalcitonin and Lung UltraSonography-based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments: study protocol for a pragmatic stepped-wedge cluster-randomized trial

Abstract Background Lower respiratory tract infections (LRTIs) are among the most frequent infections and a significant contributor to inappropriate antibiotic prescription. Currently, no single diagnostic tool can reliably identify bacterial pneumonia. We thus evaluate a multimodal approach based o...

Full description

Bibliographic Details
Main Authors: Cécile Bessat, Roland Bingisser, Markus Schwendinger, Tim Bulaty, Yvan Fournier, Vincent Della Santa, Magali Pfeil, Dominique Schwab, Jörg D. Leuppi, Nicolas Geigy, Stephan Steuer, Friedemann Roos, Michael Christ, Adriana Sirova, Tanguy Espejo, Henk Riedel, Alexandra Atzl, Fabian Napieralski, Joachim Marti, Giulio Cisco, Rose-Anna Foley, Melinée Schindler, Mary-Anne Hartley, Aurélie Fayet, Elena Garcia, Isabella Locatelli, Werner C. Albrich, Olivier Hugli, Noémie Boillat-Blanco, for the PLUS-IS-LESS study group
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Trials
Subjects:
Lower respiratory tract infection
Community-acquired pneumonia
Lung ultrasound
Procalcitonin
Antibiotic prescription
Algorithm
Online Access:https://doi.org/10.1186/s13063-023-07795-y

Internet

https://doi.org/10.1186/s13063-023-07795-y

Similar Items